PLGA Nanoparticles, Fluorescently Labeled

Description

Fluorescent PLGA Nanoparticles

Our single-layer poly (lactic-co-glycolic acid) (PLGA) nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Dye molecules are encapsulated inside the hydrophobic core to create these fluorescent PLGA nanoparticles.

PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry).

Features

• Made with FDA approved biocompatible and biodegradable PLGA polymer.
• Conjugation-ready for covalent attachment of biomolecules.
• High degree of monodispersity.
• Labeled with a fluorescent dye.
• (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
• (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

Applications

• Fluorescence labeled nanoparticles for in vitro and in-vivo targeting.
• Fluorescence imaging for in vitro and in vivo applications.
• Fluorescence probes for flowcytometry analysis.
• In vitro and in vivo delivery of proteins and small molecules.

Product is supplied as lyophilized powder.

Supplier Luna Nanotech’s page on fluorescent PLGA nanoparticles

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