PLGA Nanoparticles, Magnetic, Fluorescently Labeled

Description

Fluorescent Magnetic Nanoparticles

Our single-layer poly (lactic-co-glycolic acid) (PLGA) fluorescent magnetic nanoparticles form nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Dye molecules and magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry).

Features

• Made with FDA approved biocompatible and biodegradable PLGA polymer.
• Conjugation-ready for covalent attachment of biomolecules.
• High degree of monodispersity.
• Can be pulled down by application of magnetic force.
• Labeled with a fluorescent dye.
• (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
• (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

Applications

• Dual labeled fluorescence and magnetic nanoparticles for in-vivo tar-geting.
• Dual fluorescence and MRI imaging for in vitro and in vivo applications.
• Dual labeled fluorescence and magnetic probes for magnetic cell pull-down and flowcytometry analysis.
• In vitro and in vivo delivery of proteins and small molecules.

Product is supplied as lyophilized powder.

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