PLGA Nanoparticles, Magnetic, Carboxyl, Azide PEG

Description

PLGA Nanoparticles Magnetic

PLGA nanoparticles magnetic are created from nanostructures with a hydrophobic core encapsulated inside a hydrophilic shell. Magnetic nanoparticles are encapsulated inside the hydrophobic core. PLGA surface contains COOH groups that can be used for EDC/NHS based bioconjugation. Optional surface modifications include methoxy PEG (improves in vivo blood half-life) and PEG-Azide (can be used to covalently attach biomolecules by click chemistry)

Features

• Made with FDA approved biocompatible and biodegradable PLGA polymer.
• Conjugation-ready for covalent attachment of biomolecules.
• High degree of monodispersity.
• Can be pulled down by application of magnetic force.
• (Optional) Incorporation of Methoxy-PEG minimizes non-specific protein adsorption. This increase nanoparticle in-vivo blood half-life.
• (Optional) Incorporation of Azide-PEG allows conjugation of proteins and small molecules by click chemistry.

Applications

• Magnetic nanoparticles for in-vivo targeting.
• Probes for MRI imaging for in vitro and in vivo applications.
• Magnetic probes for magnetic cell and small molecule pulldown.
• In vitro and in vivo delivery of proteins and small molecules.

Product is supplied as lyophilized powder.