Dextran CLIO Magnetic Nanoparticles – Fluorescent Dye

Description

Fluorescent Magnetic Nanoparticles, Dextran Coated

Fluorescent dye functionalized Dextran coated crosslinked iron oxide nanoparticles (CLIO-DYE) have 1-3 superparamagnetic Fe3O4 iron oxide cores (8-10 nm in diameter) imbedded within the matrix of dextran sugar strands of 40 kDa or 70 kDa size. Dextran strands are crosslinked to prevent their disassociation, ensuring long-term biological stability. Fluorophores are covalently conjugated to the nanoparticle surface.

Features

• Highly magnetic
• Highly biocompatible, non-toxic
• Fluorescently labeled (AFDye 488, AFDye 555, AFDye 647, or IR750 dye)
• Long term stable under physiological conditions
• 40 kDa and 70 kDa dextran coats are available
• Dual-modality magnetic and fluorescence probes

Applications

• Dual-modality probes for MRI and Fluorescence imaging
• In vitro and in vivo labels for cells and tissues
• Dual magnetic and florescence cell separation

Specifications

• Iron Oxide Core Diameter: 8 – 10 nm
• Hydrodynamic Diameter: 60 – 80 nm
• Polydispersity Index (PDI): < 0.25
• Nanoparticle Charge: Between -3 and -0.3 mV
• Magnetization:  5 – 30 emu/g (room temperature)
• Fluorescent dye: AFDye 488, AFDye 555, AFDye 647, or IR750
• Shelf life: > 1 year (4°C storage)
• Supplied as liquid suspension in water

Datasheet – Fluorescent magnetic nanoparticles

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